Cervical Intraepithelial Neoplasia (CIN1, CIN2, CIN3)JAMA Dysplasia of the cervical epithelium, often premalignant (ie, cancerous), characterized by various
degrees of hyperplasia, abnormal keratinization (forming horny epidermal tissue), and condylomata.
Considerable evidence implicates human papilloma virus (HPV) in the development of CIN.
Immunosuppression may also play an important role in facilitating infection or
persistence of HPV in the genital tract and progression of HPV-induced neoplasia. See also Cervix; Condyloma; Dysplasia; Epithelium; Hyperplasia; Neoplasm.
Cervical Intraepithelial Neoplasia (CIN):SFAF
abnormal growth of
cells of the uterine cervix, suggesting an early stage of cervical cancer.
Human papillomavirus (HPV) and HIV infection are associated with an increased
risk of CIN. There are 3 grades of severity: CIN I, CIN II and CIN III.
A newer classification system divides these 3 classes into 2 categories:
low-grade and high-grade squamous intraepithelial lesion (SIL). See also
cervical dysplasia, squamous intraepithelial lesion.
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