TranscriptionJAMA The process of constructing a messenger RNA molecule using a DNA molecule as a template with the resulting transfer of genetic information to the messenger RNA. As related to HIV: The process by which the provirus produces new viruses. RNA copies called messenger RNA must be made that can be read by the host cell's protein-making machinery. Transcription is facilitated by cellular enzymes, including RNA polymerase II. The viral genes may partly control this process; tat, for example, encodes a protein that accelerates the transcription process by binding to a section of the newly made viral RNA. See also Integration; Messenger RNA; TAT; Template.
the first step in protein synthesis and replication.
Genetic information encoded in DNA is copied to messenger RNA, which is
used as a template for the production of new proteins.
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