Index:   Untitled T# -TH     Untitled TI -TQ     Untitled TR -TZ    
  • Tumor Necrosis Factor (TNF, Cachectin): SFAF
    a cytokine, produced by activated monocytes and macrophages, that can destroy tumors. When chronically elevated (as may occur in HIV disease), TNF-alpha may lead to fever, anorexia, hypermetabolism and wasting. TNF-alpha may block the production of enzymes that digest fats, leading to the breakdown of muscle tissue. In laboratory tests TNF-alpha has been shown to stimulate HIV replication. Some drugs (e.g., thalidomide, ketotifen) reduce TNF-alpha levels. TNF-beta is released by CD4 and CD8 T-cells when stimulated by an antigen. Verify TNF-Beta.

  • Click on Untitled Sources to find source(s) of the term definition cited above (see superscript).

  • Untitled If the term you are looking for is not included in this glossary/dictionary, search

  • ...