Tuberculosis (TB)JAMA A bacterial infection caused by Mycobacterium tuberculosis. TB bacteria are spread by airborne droplets expelled from the lungs when a person with active TB coughs, sneezes, or speaks. Repeated exposure to these droplets can lead to infection in the air sacs of the lungs. The immune defenses of healthy people usually prevent TB infection from spreading beyond a very small area of the lungs. If the body's immune system is impaired because of infection with HIV, aging, malnutrition, or other factors, the TB bacterium may begin to spread more widely in the lungs or to other tissues.
an infectious disease caused by Mycobacterium
tuberculosis that typically affects the lungs, but may also occur in other
organs (extrapulmonary TB). Transmission generally occurs through inhalation
of aerosolized sputum droplets. A combination of 4 chemotherapeutic drugs
is standard therapy. Multidrug-resistant tuberculosis (MDR-TB) is resistant
to several standard drugs and requires more aggressive treatment.
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