a marker or sign that can serve in place of
a clinical endpoint such as such as the disease progression or death.
Surrogate markers for HIV disease may virologic (e.g., viral load), immunologic
(e.g., CD4 cell count) or clinical (e.g., weight loss).
Surrogate MarkerJAMA A substitute; a person or thing that replaces another. In HIV disease, the number of CD4+ T cells and
CD8+ cells is a surrogate immunological marker of disease progression. See also CD4 (T4) or CD4+
CELLS; CD8 (T8) Cells.
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