RetrovirusJAMA Viruses, such as HIV, that carry their genetic material in the form of RNA (rather than DNA present in other viruses) and have the unique enzyme reverse transcriptase, not found in other viruses.
A retroviruses, such as HIV, uses the unique retroviral enzyme called reverse transcriptase (not found in other types of viruses) to convert its RNA into DNA, which is then integrated into the host cell DNA.
Like all viruses, a retrovirus, such as HIV, can replicate only inside cells, commandeering the host cell's machinery to reproduce. In the case of retroviruses -- with the integrated viral DNA (in the host cell DNA) as template -- initiates to production of the viral regulatory proteins as well as the unique retroviral enzyme called reverse transcriptase. The complex process occuring in the host cell leads to synthesis of multiple copies of viral RNAs, as well as the array of the viral package proteins. Using the host cell's machinery, the appropriate array of viral package proteins envelopes the viral RNA to produce new copies of the retrovirus.
See also DNA; Reverse Transcriptase; Ribonucleic Acid (RNA).
a class of viruses that have their genetic material
in the form of RNA and use the reverse transcriptase enzyme to transcribe
their RNA into DNA. The retrovirus family includes spumaviruses, oncoviruses
(e.g., HTLV-1) and lentiviruses (e.g., HIV-1, HIV-2).
to find source(s) of the term definition cited above (see superscript).
If the term you are looking for is not included in this glossary/dictionary, search