a trial of an experimental therapy
in which an inactive substance or mock therapy (placebo) is given to one
group while the treatment under study is given to another; the results
obtained in the different groups are then compared. Placebo is used to
make the experience of the treatment and control group as similar as possible
and to minimize bias due to the expectations of the patient or investigator.
Contrast with uncontrolled trial.
Placebo Controlled StudyJAMA A method of investigation of drugs in which an inactive substance (the placebo) is given to one group
of patients, while the drug being tested is given to another group. The results obtained in the two groups then
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