Major Histocompatibility Complex (MHC):SFAF
a group of genes that
control the expression of cell surface protein markers (also known as
human leukocyte antigen or HLA markers) that determine receptor shape
and allow immune cells to recognize components of the body (i.e., to distinguish
"self" from "non-self"). MHC molecules are necessary
for antigen presentation and for recognition of antigens by immune system
cells. Each individual has one of a variety of genetically-determined
MHC/HLA patterns. There are two classes of MHC molecules, MHC-I and MHC-II.
Major Histocompatibility Complex (MHC)JAMA A group of genes that control aspects of the immune response. The products of these genes, the histocompatibility antigens, are present on every cell of the body and serve as markers to distinguish "self" from "nonself" cells. See also Antigen; Histocompatibility Testing.
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