MacrophageJAMA A large immune cell that devours invading pathogens and other intruders. Stimulates other immune cells by presenting them with small pieces of the invader. Macrophages can harbor large quantities of HIV without being killed, acting as reservoirs of the virus.
a large scavenger white blood cell that ingests and
processes degenerated cells and foreign particles, and exhibits pieces
of the ingested matter on their surface for recognition by T-cells. Macrophages
secrete messenger proteins (monokines) involved in a variety of immune
system responses. Macrophages are derived from monocytes that leave the
blood to migrate into the tissues. The long-lived macrophages are a major
reservoir of HIV infection.
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