HIV DiseaseJAMA Characterized by a gradual deterioration of immune function. During the course of infection, crucial immune cells called CD4+ T cells are disabled and killed, and their numbers progressively decline. CD4+ T cells play a crucial role in the immune response, signaling other cells in the immune system to perform their special functions. See also Acquired Immunodeficiency Syndrome; CD4 (T4) or CD4+ Cells; Human Immunodeficiency Virus Type 1.
a disease caused by infection with the human immunodeficiency
virus (HIV). The disease is typically slow to develop and progresses from
asymptomatic to symptomatic (formerly known as AIDS-related complex or
ARC) to full-blown AIDS, a condition in which the immune system is seriously
compromised and unable to fight opportunistic pathogens.
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