a type of clinical trial in which neither the subject
nor the investigator knows what treatment, if any, the subject is receiving.
At the end of the trial the "code" is broken and data are analyzed.
Double-blinding is done to minimize bias due to the expectations of the
subject, investigator(s) and/or healthcare provider(s).
Double-blind StudyJAMA A clinical trial design in which neither the participating individuals nor the study staff know which
patients are receiving the experimental drug and which are receiving placebo or another therapy. Double-
blind trials are thought to produce objective results because the doctor's and patient's expectations about the
experimental drug do not affect the outcome. See also Clinical Trial; Placebo.
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