an infection caused by a yeast-like fungus, typically
Cryptococcus neoformans, found in soil and bird feces. A common manifestation
is cryptococcal meningitis (CM), an inflammation of the membranes surrounding
the brain and spinal cord; cryptococcosis may also become disseminated.
Symptoms may include nausea, fever, headache, dizziness, stiff neck, vision
and speech difficulties, changes in mental status, increased intracranial
pressure and seizures; untreated CM can lead to coma and death. Cryptococcosis
may also affect the lungs and may become disseminated, resulting in a
red skin rash. Treatments include oral fluconazole and amphotericin B.
CryptococcosisJAMA An infectious disease seen in HIV-infected patients due to the fungus Cryptococcus neoformans,
which is acquired via the respiratory tract. It can spread from the lungs to the brain, central nervous
system, skin, skeletal system, and urinary tract. See also Cryptococcal Meningitis.
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