CD NomenclatureJAMA This nomenclature was developed to standardize and compare monoclonal antibodies from different sources. Antibodies with similar reactivity patterns are assigned to CD groups representing "clusters of differentiation." T lymphocytes are CD3+ and can be separated into the CD4+ T helper cells and the CD8+ cytotoxic/suppressor cells. Although CD4+ cells are predominantly T lymphocytes, some monocytes are also CD4+.
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