Index:   Untitled A# - AG     Untitled AH - AM     Untitled AN - AO     Untitled AP - AZ
    Azidothymidine, also called RetrovirTM, zidovudine, or ZDV. The first antiretroviral (see) drug against HIV infection to be approved by the FDA (1987). A thymidine (RNA constituent) analog that suppresses replication of HIV. AZT is increasingly administered in combination with other antiviral drugs. Possible side effects include bone marrow suppression leading to anemia, leukopenia, or neutropenia; nausea; muscle weakness; and headaches. See Nucleoside Analog; Ribonucleic Acid.
  • AZT (Zidovudine [ZDV], Azidothymidine, Retrovir): SFAF
    a nucleoside (thymidine) analog drug that suppresses the replication of HIV by terminating DNA synthesis. AZT is FDA-approved for the treatment of HIV infection; current practice favors the use of AZT in combination with other antiretroviral drugs. AZT crosses the blood-brain barrier and may be effective against AIDS dementia complex. Adverse side effects include nausea, myopathy and bone marrow suppression.

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